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Old 01-30-2016, 06:23 PM
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kiwi33 kiwi33 is offline
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kiwi33 kiwi33 is offline
Grand Magnate
kiwi33's Avatar
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
10 yr Member
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DavidHC, you are right - there are many TTR mutants which form amyloid fairly quickly. Even normal (wild-type) TTR can do this, though slowly - this is associated with Senile Systemic Amyloidosis, which mainly affects people who are 80+ and often leads to heart damage.

I think that, if only for your peace of mind, getting checked out for all of those possible mutants is a good idea.

It could be done in two ways; sequencing both of your TTR genes or doing a SNP (Single Nucleotide Polymorphism) screen. The latter is what 23andMe does, though there may be other entities who can also do that.

Your neurologist should be able to advise you about this.
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